Article

Network-Based Biomarkers Enable Cross-Disease Biomarker Discovery

2018-03-27

Abstract excerpt

Biomarkers lie at the heart of precision medicine, biodiversity monitoring, agricultural pathogen detection, amongst others. Surprisingly, while rapid genomic profiling is becoming ubiquitous, the development of biomarkers almost always involves the application of bespoke techniques that cannot be directly applied to other datasets. There is an urgent need for a systematic methodology to create biologically-interp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d03c889-5695-5cd1-9f2c-95d4b6e3f1a0
DOI: 10.1101/289934

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Network-Based Biomarkers Enable Cross-Disease Biomarker DiscoveryDOI 10.1101/289934Read

Subnetwork-based prognostic biomarkers exhibit performance and robustness superior to gene-based biomarkers in breast cancerSemantic proximity Read

<i>PatientProfiler:</i> A network-based approach to personalized medicineSemantic proximity Read

Assessment of network module identification across complex diseases.Semantic proximity Read

Core module biomarker identification with network exploration for breast cancer metastasisSemantic proximity Read

Diagnosing phenotypes of single-sample individuals by edge biomarkers.Semantic proximity Read

ENCAPP: elastic-net-based prognosis prediction and biomarker discovery for human cancersSemantic proximity Read

Open Community Challenge Reveals Molecular Network Modules with Key Roles in DiseasesSemantic proximity Read

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.Semantic proximity Read

NetG2P: Network-based genotype-to-phenotype transformation identifies key signaling crosstalk for prognosis in pan-cancer study.Semantic proximity Read

A Systems Biology Approach to Unveil Shared Therapeutic Targets and Pathological Pathways Across Major Human CancersSemantic proximity Read

Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction networkSemantic proximity Read

Integrating genetic and gene expression data in network-based stratification analysis of cancersSemantic proximity Read