Are We Going to the Dogs? Human Disease Phenotypes in Canines

Abstract excerpt

Companion dogs are increasingly recognized as translational models for studying human physiology and disease. Unlike conventional or genetically engineered laboratory models, dogs are outbred, immunocompetent animals that spontaneously develop complex diseases whose pathogenesis and environmental exposures commonly overlap with those of humans. These distinctive features create opportunities to study mechanisms of...

Topics

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• Breeding
• Disease Models, Animal
• Dog Diseases
• Dogs
• Genome, Human
• Genomics
• Mice
• Mutation

Identifiers and source

Literature Corpus work

3c0a4a2a-cca1-5f40-a2e7-223eeada2847

DOI

10.20944/preprints202604.1132.v2