Back to search

Article

Zinc Promotes Mitochondrial Health Through PGC-1alpha Enhancing Bacterial Clearance in Macrophages Infected with Mycobacterium avium Complex

2025-07-17

Abstract excerpt

Mitochondria are increasingly recognized as important contributors to immune function in addition to energy production. They do this through modulation of various signaling pathways that regulate cellular metabolism and immune function in response to pathogens. Peroxisome proliferator-activated receptor (PPAR) coactivator 1 alpha (PGC-1) is the primary transcription factor and regulator involved in mitochondrial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3beb6c27-69ad-5120-9050-01da1e58c38c
DOI
10.20944/preprints202507.1488.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Zinc Promotes Mitochondrial Health Through PGC-1alpha Enhancing Bacterial Clearance in Macrophages Infected with Mycobacterium avium ComplexDOI 10.20944/preprints202507.1488.v1
PGC-1α activation to enhance macrophage immune function in mycobacterial infectionsSemantic proximity
Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosisSemantic proximity
Divalent Metal Uptake and the Role of ZIP8 in Host Defense Against PathogensSemantic proximity
Mechanisms and Therapeutic Potential of Nutritional ImmunitySemantic proximity
Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copperSemantic proximity
Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human MacrophagesSemantic proximity
Mitochondrial metabolic regulation of macrophage polarization in osteomyelitis and other orthopedic disorders: mechanisms and therapeutic opportunitiesSemantic proximity
Copper homeostasis; A rapier between mycobacteria and macrophagesSemantic proximity
Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosisSemantic proximity
Mitochondria: Powering the Innate Immune Response to Mycobacterium tuberculosis Infection.Semantic proximity
Comparative Roles of ZIP and ZnT Zinc Transporters in Metabolic InflammationSemantic proximity
How metals fuel fungal virulence, yet promote anti-fungal immunitySemantic proximity
Select a neighboring publication to make it the new centre.