Article

Annotation and differential analysis of alternative splicing using <i>de novo</i> assembly of RNAseq data

2016-09-12

Abstract excerpt

Genome-wide analyses reveal that more than 90% of multi exonic human genes produce at least two transcripts through alternative splicing (AS). Various bioinformatics methods are available to analyze AS from RNAseq data. Most methods start by mapping the reads to an annotated reference genome, but some start by a de novo assembly of the reads. In this paper, we present a systematic comparison of a mapping-first ap...

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Literature Corpus work: 3bcb3769-2a82-5641-813a-5023b91c2b10
DOI: 10.1101/074807

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