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Article

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence

2023-04-05

Abstract excerpt

In this study, we demonstrate the utility of whole-slide CyCIF (tissue-based cyclic immunofluorescence) imaging for characterizing immune cell infiltrates in immune checkpoint inhibitor (ICI)-induced dermatologic adverse events (dAEs). We analyzed six cases of ICI-induced dAEs, including lichenoid, bullous pemphigoid, psoriasis, and eczematous eruptions, comparing immune profiling results obtained using both stand...

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Literature Corpus work
3bba21d0-4413-5119-8db0-549a134ea399
DOI
10.1101/2023.04.03.535435
Open publication

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Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic ImmunofluorescenceDOI 10.1101/2023.04.03.535435
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