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Article

Advances in 3D cell culture for liver preclinical studies.

Acta biochimica et biophysica Sinica - 21 May 2021

Yao Ting, Zhang Yi, Lv Mengjiao, Zang Guoqing, Ng Soon Seng, Chen Xiaohua

Abstract excerpt

The 3D cell culture model is an indispensable tool in the study of liver biology in the field of health and disease and the development of clinically relevant products for liver therapies. The 3D culture model captures critical factors of the microenvironmental niche required by hepatocytes for exhibiting optimal phenotypes, thus enabling the pursuit of a range of preclinical studies that are not entirely...

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PMID: 33973620
DOI: 10.1093/abbs/gmab046

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