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Article

Population Pharmacokinetics Study of Morinidazole in Patients with Moderate Hepatic Impairment

2018-05-02

Abstract excerpt

<h4>Objective</h4> Morinidazole is a novel third generation 5-nitroimidazole antimicrobial drug which has demonstrated substantial antibacterial activity against clinical isolates of anaerobe. The aim of this study was to build population pharmacokinetic (PPK) model of morinidazole among patients with hepatic impairment and to provide dosage adjustment strategy for morinidazole in patients with hepatic impairment...

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Literature Corpus work
3b9d502b-da2e-56f6-b224-2f9ca409636f
DOI
10.1101/312728
Open publication

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