Article

Dysfunction of Torr causes a Harlequin-type ichthyosis-like phenotype in <i>Drosophila melanogaster</i>

2019-08-13

Abstract excerpt

Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an extracellular coat, the cuticle, that plays a major role in protection against exaggerated water loss. Here, we report that the ABC transporter Torr - a human ABCA12 paralog - contributes to the waterproof barrier function of the cuticle in the fruit fly Drosophila melanogaster . We show that the reduction or elimina...

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Identifiers and source

Literature Corpus work: 3b355d22-ce14-5432-8f85-469980ee3619
DOI: 10.1101/734400

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