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Hair follicles modulate skin barrier function

26 Jun 2024

Abstract excerpt

Our skin provides a protective barrier that shields us from our environment. Barrier function is typically associated with the interfollicular epidermis; however, whether hair follicles influence this process remains unclear. Here, we utilize a potent genetic tool to probe barrier function by conditionally ablating a quintessential epidermal barrier gene, Abca12, which is mutated in the most severe skin barrier...

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PMID: 38941190
DOI: 10.1016/j.celrep.2024.114347

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