Article

Metagenomic next-generation sequencing Reveals Respiratory flora distribution in COVID-19

2025-08-19

Abstract excerpt

<title>Abstract</title> <p>This retrospective study compared metagenomic next-generation sequencing (mNGS) and traditional culture for pathogen detection in 43 patients with lower respiratory tract infections (LRTI), including 34 COVID-19 cases (14 critical, 20 non-critical) and 9 non-COVID controls. mNGS demonstrated superior sensitivity (95.35% vs. 81.08%) and broader pathogen coverage, identifying 36.36% of ba...

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Literature Corpus work: 3af852ed-7bf0-5bee-a14e-48a8a03481a8
DOI: 10.21203/rs.3.rs-7116247/v1

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