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Altered microbiota of the lower respiratory tract and its association with COVID-19 severity analysed by metagenomics and metatranscriptomics

26 May 2025

Abstract excerpt

The interaction between gut and oropharyngeal microbiota plays a significant role in the viral infections like SARS-CoV-2, but role of the lower respiratory tract microbiota remains unclear. Our study utilized metatranscriptomics and metagenomics to analyze the microbial composition of bronchoalveolar lavage fluid and sputum samples from 116 COVID-19 patients, categorized into mild, severe, and critical groups....

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Chronic Obstructive Pulmonary Disease (COPD) Research
Gut microbiota and health
Respiratory and Cough-Related Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40419790
DOI: 10.1038/s42003-025-08234-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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