Article

Metagenomic next-generation sequencing Reveals Respiratory Pathogen distribution in COVID-19

2025-05-23

Abstract excerpt

<title>Abstract</title> <p>This retrospective study compared metagenomic next-generation sequencing (mNGS) and traditional culture for pathogen detection in 43 patients with lower respiratory tract infections (LRTI), including 34 COVID-19 cases (14 critical, 20 non-critical) and 9 non-COVID controls. mNGS demonstrated superior sensitivity (95.35% vs. 81.08%) and broader pathogen coverage, identifying 36.36% of ba...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0890b49e-b764-5da5-b05c-d7e79f0d2fcb
DOI: 10.21203/rs.3.rs-6482087/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Metagenomic next-generation sequencing Reveals Respiratory Pathogen distribution in COVID-19DOI 10.21203/rs.3.rs-6482087/v1Read

Metagenomic next-generation sequencing Reveals Respiratory flora distribution in COVID-19Semantic proximity Read

Clinical utility of metagenomic next-generation sequencing in pathogen detection for lower respiratory tract infectionsSemantic proximity Read

Improving Suspected Pulmonary Infection Diagnosis by Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing: a Multicenter Retrospective StudySemantic proximity Read

Metagenomic Next-generation Sequencing Indicates More Precise Pathogens in patients with pulmonary infection: a retrospective studySemantic proximity Read

Clinical utility of Metagenomic Next-Generation Sequencing on bronchoalveolar lavage fluid in diagnosis of Lower Respiratory Tract InfectionsSemantic proximity Read

Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infectionSemantic proximity Read

Diagnosis value of targeted and metagenomic sequencing in respiratory tract infectionSemantic proximity Read

Metagenomics Reveals Pathogenic Diversity and Temporal Dynamics in Severe Pneumonia Among Patients in Adult Intensive Care UnitSemantic proximity Read

Comparative performance of three next-generation sequencing techniques in real clinical lower respiratory tract infectionsSemantic proximity Read

Application of metagenomic next-generation sequencing in pathogen detection of lung infectionsSemantic proximity Read

The application prospect of metagenomic next-generation sequencing technology in diagnosing suspected lower respiratory tract infectionsSemantic proximity Read

Noninvasive diagnosis of secondary infections in COVID-19 by sequencing of plasma microbial cell-free DNASemantic proximity Read