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Laser Desorption Rapid Evaporative Ionisation Mass Spectrometry (LD-REIMS) demonstrates a direct impact of hypochlorous acid stress on PQS-mediated quorum sensing in <i>Pseudomonas aeruginosa</i>

2023-10-13

Abstract excerpt

<h4>ABSTRACT</h4> To establish infections in human hosts, Pseudomonas aeruginosa must overcome innate immune generated oxidative stress, such as the hypochlorous acid (HOCl) produced by neutrophils. We set out to find specific biomarkers of oxidative stress through the development of a protocol for the metabolic profiling of P. aeruginosa cultures grown in the presence of different oxidants using a novel ionisa...

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Literature Corpus work
3ac595ef-2dc2-5fc3-9b76-aed2579fd139
DOI
10.1101/2023.10.11.561961
Open publication

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Laser Desorption Rapid Evaporative Ionisation Mass Spectrometry (LD-REIMS) demonstrates a direct impact of hypochlorous acid stress on PQS-mediated quorum sensing in <i>Pseudomonas aeruginosa</i>DOI 10.1101/2023.10.11.561961
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