Article

The Omicron variant mutation at position 28,311 in the SARS-CoV-2 N gene does not perturb CDC N1 target detection

2021-12-17

Abstract excerpt

The emergence of new SARS-CoV-2 variants necessitates the reevaluation of current COVID-19 tests to ensure continued accuracy and reliability. The new SARS-CoV-2 variant, Omicron, is heavily mutated, with over 50 mutations within its RNA genome. Any of these mutations could adversely affect the ability of diagnostic assays to detect the virus in patient samples, potentially leading to inconclusive or false negativ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3a8fa89c-0930-56fe-869b-27d67990cff2
DOI: 10.1101/2021.12.16.21267734

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

The Omicron variant mutation at position 28,311 in the SARS-CoV-2 N gene does not perturb CDC N1 target detectionDOI 10.1101/2021.12.16.21267734Read

The Omicron variant BQ.1* with mutations at positions 28,311 and 28,312 in the SARS-CoV-2 N gene have minimal impact on CDC N1 target detectionSemantic proximity Read

Analytical Sensitivity of the SalivaDirect™ Assay on the Liberty16 for detecting SARS-CoV-2 B.1.1.529 (“Omicron”)Semantic proximity Read

SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene.Semantic proximity Read

Molecular detection of SARS‐CoV‐2 and differentiation of Omicron and Delta variant strainsSemantic proximity Read

PCR performance in the SARS-CoV-2 Omicron variant of concern?Semantic proximity Read

Rapid Detection of the Omicron (B.1.1.529) SARS-CoV-2 Variant Using a COVID-19 Diagnostic PCR Assay.Semantic proximity Read

In silico evaluation of the impact of the Omicron variant on the sensitivity of RT-qPCR assays for SARS-CoV-2 detection using whole genome sequencingSemantic proximity Read

Sensitivity of SARS-CoV-2 antigen-detecting rapid tests for Omicron variantSemantic proximity Read