Article
PCR performance in the SARS-CoV-2 Omicron variant of concern?
Swiss medical weekly - 6 Dec 2021
Metzger César M J A, Lienhard Reto, Seth-Smith Helena M B, Roloff Tim, Wegner Fanny, Sieber Jonas, Bel Michael, Greub Gilbert, Egli Adrian
Abstract excerpt
The new SARS-CoV-2 Omicron variant (B.1.1.529) has been recently declared a Variant of Concern due to a series of important mutations in the viral spike protein and especially in the receptor-binding domain. While investigations into the spread of this new variant are ongoing, the first cases have been detected in Switzerland. Important questions have been raised: (1) Will the PCR assays commonly used to detect...
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