Article

A distinct class of conjugative megaplasmids includes potential vehicles for prophage dissemination

2026-02-22

Abstract excerpt

Closely related prophages are frequently found in phylogenetically distant bacteria in the human gut, despite limited evidence of productive phage infections across broad host ranges. Thus, it remains unclear how the wide distribution of prophages could emerge. Here, we identify a potential mechanism of prophage dissemination. We describe two deeply diverged groups of conjugative megaplasmids (>300 kilobases) in t...

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Literature Corpus work: 3a780051-51d1-5550-b335-ce90dd167026
DOI: 10.64898/2026.02.21.707213

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