Article

Fc effector activity and neutralization against SARS-CoV-2 BA.4 is compromised in convalescent sera, regardless of the infecting variant

2022-07-15

Abstract excerpt

<h4>Summary</h4> The SARS-CoV-2 Omicron BA.1 variant, which exhibits high level neutralization resistance, has since evolved into several sub-lineages including BA.4 and BA.5, which have dominated the fifth wave of infection in South Africa. Here we assessed the sensitivity of BA.4 to neutralization and antibody dependent cellular cytotoxicity (ADCC) in convalescent donors infected with four previous variants of...

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Literature Corpus work: 3a517f73-6c7d-5f2c-baeb-05b93900b877
DOI: 10.1101/2022.07.14.500042

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