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Neutralisation hierarchy of SARS-CoV-2 Variants of Concern using standardised, quantitative neutralisation assays reveals a correlation with disease severity; towards deciphering protective antibody thresholds

2021-05-26

Abstract excerpt

<h4>Background</h4> The rise of SARS-CoV-2 variants has made the pursuit to define correlates of protection more troublesome, despite the availability of the World Health Organisation (WHO) International Standard for anti-SARS-CoV-2 Immunoglobulin sera, a key reagent used to standardise laboratory findings into an international unitage. <h4>Methods</h4> Using pseudotyped virus, we examine the capacity of convalesc...

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Literature Corpus work
bd11157d-9b8f-5172-8d27-f2c0f165f177
DOI
10.1101/2021.05.24.21257729
Open publication

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Neutralisation hierarchy of SARS-CoV-2 Variants of Concern using standardised, quantitative neutralisation assays reveals a correlation with disease severity; towards deciphering protective antibody thresholdsDOI 10.1101/2021.05.24.21257729
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