Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amplification-free, OR-gated CRISPR-Cascade reaction for pathogen detection in blood samples

10 Mar 2025

Abstract excerpt

Rapid and accurate detection of DNA from disease-causing pathogens is essential for controlling the spread of infections and administering timely treatments. While traditional molecular diagnostics techniques like PCR are highly sensitive, they include nucleic acid amplification and many need to be performed in centralized laboratories, limiting their utility in point-of-care settings. Recent advances in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to CRISPR and Genetic Engineering
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40063799
DOI: 10.1073/pnas.2420166122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amplification-free, OR-gated CRISPR-Cascade reaction for pathogen detection in blood samplesPMID 40063799Read ↗

CRISPR-based diagnostics.Semantic proximity Read ↗

Nucleic Acid Detection Using CRISPR/Cas Biosensing TechnologiesSemantic proximity Read ↗

CRISPR-Cas-based techniques for pathogen detection: Retrospect, recent advances, and future perspectivesSemantic proximity Read ↗

CRISPR Approaches for the Diagnosis of Human DiseasesSemantic proximity Read ↗

Recent Improvements in CRISPR-Based Amplification-Free Pathogen DetectionSemantic proximity Read ↗

CRISPR-cas technology: A key approach for SARS-CoV-2 detectionSemantic proximity Read ↗

From Lab to Life: The Rise of CRISPR-Based Diagnostics for Point-of-Care and Global HealthSemantic proximity Read ↗

CRISPR/Cas-based nucleic acid detection strategies: Trends and challengesSemantic proximity Read ↗

The CRISPR–Cas toolbox for analytical and diagnostic assay developmentSemantic proximity Read ↗

CRISPR-Based COVID-19 Testing: Toward Next-Generation Point-of-Care DiagnosticsSemantic proximity Read ↗

Point-of-Care Pathogen Detection with CRISPR-based Programmable Nucleic Acid Binding Proteins.Semantic proximity Read ↗

Programmable Biosensors Based on RNA-Guided CRISPR/Cas EndonucleaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.