Article

TNF-α–Driven NOX5 Activation Promotes Oxidative Stress and Umbilical Artery Dysfunction in Preeclampsia

2026-05-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Preeclampsia (PE) is a hypertensive disorder of pregnancy characterized by systemic inflammation, oxidative stress, and endothelial dysfunction. Although maternal vascular dysfunction is well established in PE, the mechanisms underlying fetal vascular injury remain poorly understood. We investigated whether inflammatory signaling activates NADPH oxidase 5 (NOX5) and contribu...

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Literature Corpus work: 39f61de6-7e8a-5d16-911f-d412d0a6d4ed
DOI: 10.64898/2026.05.18.726116

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