Article

Predicting survival in prospective clinical trials using weakly-supervised QSP

2024-10-21

Abstract excerpt

<title>Abstract</title> <p>Quantitative systems pharmacology (QSP) models of cancer immunity offer a mechanistic understanding of cellular dynamics and drug effects that are often challenging to investigate clinically. Despite their success, these models are limited by their inability to mechanistically represent patient survival as an output, which restricts their utility in the clinical development of anti-canc...

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Literature Corpus work: 39b26f56-0219-57b2-932e-13f03d08c3fd
DOI: 10.21203/rs.3.rs-4838339/v1

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