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Variable Number Tandem Repeats (VNTRs) as modifiers of breast cancer risk in carriers of <i>BRCA1</i> 185delAG

2022-06-02

Abstract excerpt

Despite substantial efforts in identifying both rare and common variants affecting disease risk, in the majority of diseases, a large proportion of unexplained genetic risk remains. We propose that variable number tandem repeats (VNTRs) may explain a proportion of the missing genetic risk. Herein, we tested whether VNTRs are causal modifiers of breast cancer risk in 347 female carriers of BRCA1 185delAG, an impor...

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Identifiers and source

Literature Corpus work
39ac1131-0548-5dec-859a-2369dae0886f
DOI
10.1101/2022.06.01.494371
Open publication

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Variable Number Tandem Repeats (VNTRs) as modifiers of breast cancer risk in carriers of <i>BRCA1</i> 185delAGDOI 10.1101/2022.06.01.494371
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