Article

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

2009-07-06

Abstract excerpt

No abstract is available from the source.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3950988a-1b69-5696-bedd-4e2be7fdcfbd
DOI: 10.1084/jem.200819226209c
PMCID: PMC2715085

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemiaDOI 10.1084/jem.200819226209cRead

Regulation of immune cell development, differentiation and function by stromal Notch ligandsSemantic proximity Read

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathwaySemantic proximity Read

Notch1 and IL-7 Receptor Interplay Maintains Proliferation of Human Thymic Progenitors while Suppressing Non-T Cell FatesSemantic proximity Read

Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R–STAT5B-driven neoplasmsSemantic proximity Read

Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALLSemantic proximity Read

Human innate lymphoid cellsSemantic proximity Read

ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.Semantic proximity Read

IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemiaSemantic proximity Read

Group 3 innate lymphoid cells (ILC3s): Origin, differentiation, and plasticity in humans and miceSemantic proximity Read

B7 family checkpoint regulators in immune regulation and diseaseSemantic proximity Read

JAKs and STATs in immunity, immunodeficiency, and cancer.Semantic proximity Read

The Lineage Differentiation and Dynamic Heterogeneity of Thymic Epithelial Cells During Thymus OrganogenesisSemantic proximity Read