Article

Bioinformatics Approach to Identify Diseasome and Co-morbidities Effect of Mitochondrial Dysfunctions on the Progression of Neurological Disorders

2018-11-29

Abstract excerpt

Mitochondrial dysfunction can cause various neurological diseases. We therefore developed a quantitative framework to explore how mitochondrial dysfunction may influence the progression of Alzheimer’s, Parkinson’s, Huntington’s and Lou Gehrig’s diseases and cerebral palsy through analysis of genes showing altered expression in these conditions. We sought insights about the gene profiles of mitochondrial and associ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3949d6cf-326a-5f59-b6cd-814d03f717e2
DOI: 10.1101/483065

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bioinformatics Approach to Identify Diseasome and Co-morbidities Effect of Mitochondrial Dysfunctions on the Progression of Neurological DisordersDOI 10.1101/483065Read

Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases.Semantic proximity Read

The Big Picture of Neurodegeneration: A Meta Study to Extract the Essential Evidence on Neurodegenerative Diseases in a Network-Based ApproachSemantic proximity Read

Novel susceptibility genes and molecular mechanisms identified in relation to mitochondrial dysfunctions in Parkinson’s diseaseSemantic proximity Read

Common Factors in Neurodegeneration: A Meta-Study revealing Shared Patterns on a Multi-Omics ScaleSemantic proximity Read

Network approaches for omics studies of neurodegenerative diseasesSemantic proximity Read

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB SignalingSemantic proximity Read

Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's diseaseSemantic proximity Read

Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale.Semantic proximity Read

Discovering New Genes in the Pathways of Common Sporadic Neurodegenerative Diseases: A Bioinformatics Approach.Semantic proximity Read

Molecular mechanisms and biomarkers in neurodegenerative disorders: a comprehensive reviewSemantic proximity Read

An Effective Method to Identify Shared Pathways and Common Factors among Neurodegenerative Diseases.Semantic proximity Read

Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approachesSemantic proximity Read