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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease

8 Feb 2025

Abstract excerpt

BACKGROUND: There is growing evidence that the pathogenesis of Alzheimer's disease is closely linked to the resident innate immune cells of the central nervous system, including microglia and astrocytes. Mitochondrial dysfunction in microglia has also been reported to play an essential role in the pathogenesis of AD and other neurological diseases. Therefore, finding the mitochondrial and immune-related gene...

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PMID: 39920860
DOI: 10.1186/s40001-025-02297-w

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