Article

SCC <i>mec</i> transformation requires living donor cells in mixed biofilms

2023-09-11

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that has emerged through the horizontal acquisition of the staphylococcus cassette chromosome mec (SCC mec ). Previously, we showed that SCC mec from heat-killed donors can be transferred via natural transformation in biofilms at frequencies of 10 -8 -10 -7 . Here, we show an improved transformation assay of SCC mec with frequ...

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Literature Corpus work: 39432dcb-2058-51f2-9fe6-7636e1a4d168
DOI: 10.1101/2023.09.11.557198

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