Novel Staphylococcal Cassette Chromosome <i>mec</i> Type, Tentatively Designated Type VIII, Harboring Class A <i>mec</i> and Type 4 <i>ccr</i> Gene Complexes in a Canadian Epidemic Strain of Methicillin-Resistant <i>Staphylococcus aureus</i>

Abstract excerpt

Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element characterized by flanking terminal direct and, in most cases, inverted repeat sequences, the mec and ccr gene complexes, and their surrounding DNA regions. Unique combinations of the mec and ccr gene complexes generate various SCCmec types. Six SCCmec types have been reported to date. We describe here a novel SCCmec type identified in a...

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