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Close, But no Cigar: Comparative Evaluation of ChatGPT-4o and OpenAI o1-preview in Answering Pancreatic Ductal Adenocarcinoma-Related Questions

2025-07-31

Abstract excerpt

<h4>Background</h4> This study aimed to evaluate the effectiveness of ChatGPT-4o and OpenAI o1-preview in responding to pancreatic ductal adenocarcinoma (PDAC)-related queries. The study assessed both LLMs’ accuracy, comprehensiveness, and safety when answering clinical questions, based on the National Comprehensive Cancer Network® (NCCN) Clinical Practice Guidelines for PDAC. <h4>Methods</h4> The study used a 2...

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Genomics and Rare Diseases

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Literature Corpus work: 39268984-23d4-507c-ad1a-3f1e37f76b4c
DOI: 10.1101/2025.07.26.25332239

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