Article

Two-sample Mendelian randomization analysis of associations between periodontal disease and risk of colorectal, lung, and pancreatic cancers

2021-01-24

Abstract excerpt

Observational studies indicate that periodontal disease may increase the risk of colorectal, lung, and pancreatic cancers. We tested these associations using two-sample Mendelian randomization to emulate a randomized study with observational data. We developed an instrument including single nucleotide polymorphisms with strong genome-wide association study evidence for associations with aggressive and/or advanced...

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Literature Corpus work: 391a6c25-1c7d-53a0-b3bf-3c84b25c2a26
DOI: 10.1101/2021.01.14.21249587

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