Article

Beyond Single Algorithms: A Framework for Validating and Aggregating Active Modules in Genetic Interaction Networks

2025-10-07

Abstract excerpt

1 High-throughput sequencing methods have generated vast amounts of genetic data for candidate gene studies. However, the complexity of the disease genetic structure often results in a large number of candidate genes and poses a significant challenge for these studies. To explore the multi-gene interactions and elucidate the genetic mechanism, candidate genes are often analyzed through Gene-Gene interaction (GGI)...

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Literature Corpus work: 39198400-5115-52f6-aa95-d45d72e3ca04
DOI: 10.1101/2025.10.06.680790

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