Article
Module representatives for refining gene co-expression modules.
Physical biology - 4 May 2023
Mankovich Nathan, Andrews-Polymenis Helene, Threadgill David, Kirby Michael
Abstract excerpt
This paper concerns the identification of gene co-expression modules in transcriptomics data, i.e. collections of genes which are highly co-expressed and potentially linked to a biological mechanism. Weighted gene co-expression network analysis (WGCNA) is a widely used method for module detection based on the computation of eigengenes, the weights of the first principal component for the module gene expression...
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