Article

excluderanges: exclusion sets for T2T-CHM13, GRCm39, and other genome assemblies

2022-11-24

Abstract excerpt

<h4>Summary</h4> Exclusion regions are sections of reference genomes with abnormal pileups of short sequencing reads. Removing reads overlapping them improves biological signal, and these benefits are most pronounced in differential analysis settings. Several labs created exclusion region sets, available primarily through ENCODE and Github. However, the variety of exclusion sets creates uncertainty which sets to...

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Literature Corpus work: 3913d8a9-a277-5714-bc5e-16da1099dcf4
DOI: 10.1101/2022.11.21.517407

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