Article

Gastrointestinal and Fluid Retention Symptoms Associated with Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation

2025-10-13

Abstract excerpt

<h4>Background</h4> Creatine monohydrate (CM) is widely used for improving athletic performance and supporting general health. Despite its well-established safety profile, gastrointestinal (GI) distress and varying issues related to fluid retention remains a commonly reported side effect, particularly at higher doses. As CM is increasingly utilized in non-athletic populations—including females who are underrepres...

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Literature Corpus work: 38fdd9b2-27c8-5bc9-8d3f-5f5bdfe5d27e
DOI: 10.1101/2025.10.07.25337280

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