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EVALUATION OF A METAGENOMIC NEXT-GENERATION SEQUENCING ASSAY WITH A NOVEL HOST DEPLETION METHOD FOR PATHOGEN IDENTIFICATION IN SEPTIC PATIENTS

2023-03-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The traditional diagnosis of sepsis has always been based on microbial blood culture (BC). However, BC suffers from (1) long culture cycle, leading to delay in results, and (2) low diagnostic yields. Metagenomic next-generation sequencing (mNGS) has been proposed as an efficient and agnostic option that potentially overcomes these issues. In this study, a mNGS workflow utilizi...

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Literature Corpus work: 38750b59-d687-5003-a13e-1adde369b98c
DOI: 10.1101/2023.03.28.23287867

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