Article

A thorough pan-cancer analysis and experimental confirmation of the function of adenylosuccinate lyase in glioma

2026-07-10

Abstract excerpt

<title>Abstract</title> <p>Background Adenylosuccinate (ADSL) lyase, a critical enzyme involved in purine metabolism, has been implicated in tumorigenesis, however, its comprehensive role across cancers and underlying mechanisms in glioma remain incompletely elucidated. Methods We performed pan-cancer analyses using datasets from The Cancer Genome Atlas, Genotype-Tissue Expression and Human Protein Atlas to eva...

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Literature Corpus work: 38121cc5-e419-54b5-8256-b5c3551fd7e4
DOI: 10.21203/rs.3.rs-9479003/v1

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