Article

LncRNA xist regulates sepsis-associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis

2023-04-20

Abstract excerpt

<h4>Background: </h4> Neuroinflammation is a common feature of many neurological diseases, and remains crucial for disease progression and prognosis. Activation of microglia and astrocytes arouse neuroinflammation. However, little is known about the role of lncRNA xist and miR-122-5p in the occurrence of sepsis-associated neuroinflammation (SAN). In this study, we aimed to investigate the role of lncRNA xist and m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 37ee6e8e-49d2-5bbc-985e-3d27912764a1
DOI: 10.21203/rs.3.rs-2793073/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

LncRNA xist regulates sepsis-associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη AxisDOI 10.21203/rs.3.rs-2793073/v1Read

Revealing the novel pyroptosis-related therapeutic targets for sepsis based on the machine learningSemantic proximity Read

Revealing novel pyroptosis-related therapeutic targets for sepsis based on machine learningSemantic proximity Read

The miRNA neuroinflammatory biomarkers in COVID-19 patients with different severity of illnessSemantic proximity Read

Cerebrospinal fluid inflammome analysis identifies host- and pathogen-specific inflammatory profiles and signaling pathways in meningitis and predicts clinical outcomeSemantic proximity Read

Identification of IL-8 in CSF as a potential biomarker in sepsis-associated encephalopathySemantic proximity Read

TNFα-Induced Endothelial Extracellular Vesicles Regulate Astrocyte Function: An Integrated Transcriptomic and Proteomic StudySemantic proximity Read

MiRNA-338-3p inhibit neuroinflammation in the corpus callosum of ICV-LPS rats via STAT1 signal pathwaySemantic proximity Read

ITGB2 and ICAM3 predict increased survival of sepsis with decreased intercellular communication in Cytotoxic CD8+ T- cellsSemantic proximity Read

Exosomes Derived From Heat Stroke Cases Carry miRNAs Associated With Inflammation and Coagulation CascadeSemantic proximity Read

MicroRNA‑146a improves sepsis‑induced cardiomyopathy by regulating the TLR‑4/NF‑κB signaling pathwaySemantic proximity Read

Molecular Regulatory Pathways Link Sepsis With Metabolic Syndrome: Non-coding RNA Elements Underlying the Sepsis/Metabolic Cross-TalkSemantic proximity Read