Article
Agent-Driven Validation of Oncology Therapeutic Targets
2026-05-03
Abstract excerpt
<h4>ABSTRACT</h4> Selecting the correct target is critical in drug development, yet systematic replication of published target claims is rarely performed. Here, we introduce a replication-focused AI agent framework to evaluate 31 gene target–disease hypotheses, including context-specific oncology targets from both retracted and non-retracted papers. Each target claim was translated into a zero-shot validation pro...
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Identifiers and source
- Literature Corpus work
- 37cebdaf-6e38-5adf-b557-6b5bdf311c19
- DOI
- 10.64898/2026.04.29.721634