Article

Convalescence from prototype SARS-CoV-2 protects Syrian hamsters from disease caused by the Omicron variant

2021-12-26

Abstract excerpt

The mutation profile of the SARS-CoV-2 Omicron variant poses a concern for naturally acquired and vaccine-induced immunity. We investigated the ability of prior infection with an early SARS-CoV-2, 99.99% identical to Wuhan-Hu-1, to protect against disease caused by the Omicron variant. We established that infection with Omicron in naïve Syrian hamsters resulted in a less severe disease than a comparable dose of pr...

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Literature Corpus work: 37c92d74-af1f-5575-98bd-609104e07a39
DOI: 10.1101/2021.12.24.474081

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