Article

Characterization of coordinated growth in macrodactyly caused by somatic mosaic activating mutations in<i>PIK3CA</i>

2022-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Localized somatic overgrowth disorders that occur during development can be debilitating, and most often require surgical intervention. Although underlying genetic changes associated with overgrowth have been identified in the majority of cases, the cause of the dysregulated growth and its presentation is unknown. Here we detail current work on a specific overgrowth disorder, macrodactyly, in whi...

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Literature Corpus work: 37c657c0-b740-5852-9dbc-2cdc2612b0f3
DOI: 10.1101/2022.06.07.22275709

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