Article

Longitudinal proteomic module configurations differ across human monocyte-derived differentiation and polarization conditions after accounting for donor and time

2026-06-26

Abstract excerpt

<h4>Background</h4> Monocytes and the cells they give rise to span a continuum of functional configurations rather than a small set of fixed types, and the M1/M2 dichotomy is now regarded as a simplification of a broader, time-dependent space. Whether a proteomic, module-level description of human monocyte-derived differentiation holds once cell identity, differentiation time and donor are separated has not been...

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Literature Corpus work: 3799cb5a-42e1-5bfd-8199-1f5baf2f88c4
DOI: 10.64898/2026.06.24.734366

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