Article
Airway microbiome–host transcriptome networks link microbial dysbiosis to survival outcomes and therapeutic opportunities in severe COVID-19
2025-06-25
Abstract excerpt
<h4>SUMMARY</h4> The lower respiratory tract microbiome may critically influence outcomes in severe COVID-19, yet remains understudied. We analyzed bronchoalveolar lavage fluid from 86 severe patients requiring mechanical ventilation, stratified into two groups. We identified 213 bacteria with differential abundance, 11 bacteria associated with differentially expressed genes, and 39 of them were associated with p...
Topics
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- Antibiotic Use and Resistance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Respiratory viral infections research
Identifiers and source
- Literature Corpus work
- 3764a71b-b62a-52f3-bdee-fac5e4538a25
- DOI
- 10.1101/2025.06.24.661228
