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Article

Airway microbiome–host transcriptome networks link microbial dysbiosis to survival outcomes and therapeutic opportunities in severe COVID-19

2025-06-25

Abstract excerpt

<h4>SUMMARY</h4> The lower respiratory tract microbiome may critically influence outcomes in severe COVID-19, yet remains understudied. We analyzed bronchoalveolar lavage fluid from 86 severe patients requiring mechanical ventilation, stratified into two groups. We identified 213 bacteria with differential abundance, 11 bacteria associated with differentially expressed genes, and 39 of them were associated with p...

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Literature Corpus work
3764a71b-b62a-52f3-bdee-fac5e4538a25
DOI
10.1101/2025.06.24.661228
Open publication

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Airway microbiome–host transcriptome networks link microbial dysbiosis to survival outcomes and therapeutic opportunities in severe COVID-19DOI 10.1101/2025.06.24.661228
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