Article

Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier

2024-09-22

Abstract excerpt

The intestinal mucosal barrier forms a critical interface between lumen contents such as bacteria, drugs, and drug carriers and the underlying tissue. Current in vitro intestinal models, while recapitulating certain aspects of this barrier, generally present challenges with respect to imaging transport across mucus and uptake into enterocytes. A human mesofluidic small intestinal chip was designed to enable facil...

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Literature Corpus work: 372c458f-f29a-574d-b1c6-8d55de84bbb4
DOI: 10.1101/2024.09.18.613692

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