Article
The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD
2021-03-09
Abstract excerpt
<h4>Summary</h4> In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal antibody responses in vaccinees were robust and comparable to or exceeded those seen after natural infection. However, the ratio of binding to neutralizing antibodies after vaccination was greater than that after natural infecti...
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Identifiers and source
- Literature Corpus work
- 36ccd5bd-dcd5-5045-bf70-99c89347187f
- DOI
- 10.1101/2021.03.07.21253098
