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The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD

2021-03-09

Abstract excerpt

<h4>Summary</h4> In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal antibody responses in vaccinees were robust and comparable to or exceeded those seen after natural infection. However, the ratio of binding to neutralizing antibodies after vaccination was greater than that after natural infecti...

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Literature Corpus work
36ccd5bd-dcd5-5045-bf70-99c89347187f
DOI
10.1101/2021.03.07.21253098
Open publication

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The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBDDOI 10.1101/2021.03.07.21253098
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