Article

TDP43 Interacts with MLH1 and MSH6 Proteins in A DNA Damage-Inducible Manner

2024-05-21

Abstract excerpt

<title>Abstract</title> <p>Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the motor neuron. One aspect of the neuropathology involved in ALS includes increased genomic damage and impaired DNA repair capability. The TAR-DNA binding protein 43 (TDP43) has been associated with both sporadic and familial forms of ALS, and is typically observed as cytosolic mislocalization of pro...

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Literature Corpus work: 3614aa90-2681-5460-b968-1a88251b799e
DOI: 10.21203/rs.3.rs-4439430/v1

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