Article

Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilative Cardiomyopathy (p.R312H and p.E361G)

2021-02-02

Abstract excerpt

<title>Abstract</title> <p>The human mutant cardiac α-actins p.A295S or p.R312H (plus p.R312K) and p.E361G correlated with hypertrophic or dilative cardiomyopathy, respectively, were expressed by using the <italic>baculovirus/Sf21</italic> insect cell system. After purification their biochemical and cell biological properties were analysed and compared to wild type (wt) cardiac actin identically obtained or conve...

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Literature Corpus work: 35d91da3-cc54-5eb3-a363-baeee9af2b52
DOI: 10.21203/rs.3.rs-159358/v1

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