Article

Induction of p53-mediated apoptosis by azacitidine in patient-derived xenograft follicular helper T-cell lymphoma model

2024-11-06

Abstract excerpt

<title>Abstract</title> <p>Follicular helper T-cell lymphoma (TFHL) is the most common non-cutaneous T-cell lymphoma in the Western world and is associated with a poor prognosis. Neoplastic cells rely heavily on the tumor microenvironment, demonstrated by the absence of TFHL-derived cell lines, which hinders therapeutic progress. To overcome this limitation, we developed and characterized patient-derived xenograf...

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Literature Corpus work: 35b4ca73-74b1-5bc5-ad5b-fa422125679d
DOI: 10.21203/rs.3.rs-5117296/v1

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