Article

A Trial of Intra-Pleural BacteriaL ImmunoTherapy In Malignant Pleural Mesothelioma (TILT) – A Randomised Feasibility Study Using The Trial Within A Cohort (TwiC) Methodology

2021-07-28

Abstract excerpt

<title>Abstract</title> <p><italic>Background</italic>Malignant pleural mesothelioma (MPM) is an aggressive thoracic malignancy with a poor prognosis. Systemic immunotherapy is an effective front-line treatment for MPM, and there is a scientific rationale supporting the possible efficacy of local i.e. intra-pleural immune modulators. TILT investigated the feasibility of performing a randomised trial of intra-pleu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 35697fb8-e36b-5283-819b-a371798cae32
DOI: 10.21203/rs.3.rs-256386/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Trial of Intra-Pleural BacteriaL ImmunoTherapy In Malignant Pleural Mesothelioma (TILT) – A Randomised Feasibility Study Using The Trial Within A Cohort (TwiC) MethodologyDOI 10.21203/rs.3.rs-256386/v2Read

Global Transportability of Clinical Trial Outcomes to Real-World Lung Cancer Populations A case Study using Lung-MAP S1400ISemantic proximity Read

Characteristics and Developmental Trajectory of Clinical Trials Focused on Tumor-Infiltrating Lymphocytes for Cancer TreatmentSemantic proximity Read

Data analysis planning and reporting for confirmatory multi-lab preclinical trialsSemantic proximity Read

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical modelsSemantic proximity Read

Real-World Data and Evidence in Lung Cancer: A Review of Recent DevelopmentsSemantic proximity Read

Management of malignant pleural mesothelioma.Semantic proximity Read

Artichoke Phytocomplex Modulates Serum microRNAs in Patients Exposed to Asbestos: A First Step of a Phase II Clinical TrialSemantic proximity Read

Practical Guidance for Running Late-Phase Platform Protocols for Clinical Trials: Lessons From Experienced UK Clinical Trials UnitsSemantic proximity Read

Acceptability of advanced Controlled Human Infection Models; the case of a pneumococcal challenge in people living with HIV and mycobacterial challenge with Bacillus Calmette Guerin in MalawiSemantic proximity Read

Experiences of participant engagement from an African and Asian ancestry cohort during a clinical research study of lymph node responses to influenza immunisation in the United KingdomSemantic proximity Read

Multicenter preclinical validation of next-generation CAR T cells: a strategy for harmonization, reproducibility, and its feasibility in clinical translationSemantic proximity Read