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Differential Patterns of Cross-Protection against Antigenically Distinct Variants in Small Animal Models of SARS-CoV-2 Infection

2024-03-15

Abstract excerpt

Continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will likely force more future updates of vaccine composition. Based on a series of studies carried out in human ACE2 transgenic mice (K18-hACE2) and Syrian hamsters, we show that immunity at the respiratory tract, acquired through either previous infection or vaccination with an in-house live attenuate virus, offers protection aga...

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Identifiers and source

Literature Corpus work
351883fe-4213-58f4-9fe5-a90d5b07b0d0
DOI
10.1101/2024.03.14.584985
Open publication

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Differential Patterns of Cross-Protection against Antigenically Distinct Variants in Small Animal Models of SARS-CoV-2 InfectionDOI 10.1101/2024.03.14.584985
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