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A Carriage-Structured Model of Meningococcal Meningitis: Backward Bifurcation, Seasonal Recurrence, and the Reach of Conjugate-Vaccine Strategies in the African Meningitis Belt

2026-08-06

Abstract excerpt

Epidemic meningococcal meningitis in the African meningitis belt recurs on two superimposed timescales: a sharp annual dry-season peak and irregular multi-annual epidemics separated by five to twelve years. Because invasive disease is a rare, epidemiologically dead-end outcome of asymptomatic nasopharyngeal carriage, transmission models built on the standard susceptible-infectious template misrepresent the driving...

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Literature Corpus work
35106838-3213-5b61-95f1-98f7bd14aee2
DOI
10.20944/preprints202608.0413.v1
Open publication

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A Carriage-Structured Model of Meningococcal Meningitis: Backward Bifurcation, Seasonal Recurrence, and the Reach of Conjugate-Vaccine Strategies in the African Meningitis BeltDOI 10.20944/preprints202608.0413.v1
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