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Integrative Analysis of Global Gene Expression Identifies Opposite Patterns of Reactive Astrogliosis in Aged Human Prefrontal Cortex

2018-10-31

Abstract excerpt

Prefrontal cortex (PFC) is one of the brain regions with more prominent changes in human aging. The molecular processes related to the aging cognitive decline and mood changes are not completely understood. In order to improve our knowledge, we integrated transcriptomic data of four studies of human PFC from old people -58-80 years old- compared with young people -20-40 years old- using a meta-analytic approximati...

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Literature Corpus work
34d38db4-3f89-55dd-be9c-9f7196e114e2
DOI
10.20944/preprints201810.0733.v1
Open publication

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Integrative Analysis of Global Gene Expression Identifies Opposite Patterns of Reactive Astrogliosis in Aged Human Prefrontal CortexDOI 10.20944/preprints201810.0733.v1
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